The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering epidemiology chemistry etc. These difficulties are particularly common in problems that have dynamic and stochastic... Lees meer.

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines numerous case studies where follow-up studi... Lees meer.

The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering epidemiology chemistry etc. These difficulties are particularly common in problems that have dynamic and stochastic... Lees meer.

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. This book provides an overview of the nonclinical testing strategies that are used to asse... Lees meer.

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Offers comprehensive coverage of currently available cancer predictors the most recent research on carcinogenicity and the design and interpretation of carcinogenicity experiments. Presents mouse rat and human carcinogenicity data for the liver kidney breast cerv... Lees meer.

Offers comprehensive coverage of currently available cancer predictors the most recent research on carcinogenicity and the design and interpretation of carcinogenicity experiments. Presents mouse rat and human carcinogenicity data for the liver kidney breast cerv... Lees meer.