The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering epidemiology chemistry etc. These difficulties are particularly common in problems that have dynamic and stochastic... Lees meer.

Right behind cardiovascular diseases cancer ranks second in causes of death in Austria. It can develop in any human tissue is characterized by an abnormal cell growth and follows a multistage development which can be divided into three steps - initiation promotion p... Lees meer.

The International Life Sciences Institute lLSI is a scientific foundation wh ich addresses critical health and safety issues of national and international concern. The International Life Sciences Institute lLSI is a scientific foundation wh ich addresses critical... Lees meer.

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines numerous case studies where follow-up studi... Lees meer.

The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering epidemiology chemistry etc. These difficulties are particularly common in problems that have dynamic and stochastic... Lees meer.

An introductory chapter deals with the mechanisms whereby a given compound reaching genetic material either directly or indirectly may increase the risk of a cancer developing in the exposed individual and of abnormalities being passed on to his or her progeny. Th... Lees meer.

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This volume consists of the proceedings of a symposium held at Oxford concerning the weight to be given to negative epidemiolgoical evidence in identifying agents that are potentially carcinogenic to humans. A number of highly pertinent examples are studied including c... Lees meer.

Cadmium is widely dispersed in the environment. Human exposure to low levels occur as a result of natural processes as well as human activities such as mining smelting fossil fuel combustion and industrial use. Pollution of the general environment by cadmium has as ye... Lees meer.

An in-depth exploration of Benzene Carcinogenicity including source measurement analysis and clinical conclusions. An in-depth exploration of Benzene Carcinogenicity including source measurement analysis and clinical conclusions.... Lees meer.

Polycyclic aromatic hydrocarbons many of which have been identified as potent human carcinogens occur widely in the environment as a result of incomplete combustion of fossil fuels and other organic matter. Major sources of emissions arise from wood and coal burning... Lees meer.

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. This book provides an overview of the nonclinical testing strategies that are used to asse... Lees meer.

... Lees meer.

This book is intended for anyone who cares about the health of people exposed to industrial pollutants. Attention is given to those pollutants which present a possible risk to the genetic material of exposed workers. Chapters are devoted to heavy metals such as arsenic... Lees meer.

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