Due to the unstable noncrystalline and insoluble nature of some proteins the technologies such as X-ray crystallography NMR nuclear magnetic resonance spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins... Lees meer.

A proven collection of readily reproducible techniques for studying amyloid proteins and their involvement in the etiology pathogenesis diagnosis and therapy of amyloid diseases. In recent years various in vitro and in vivo techniques transgenic technologies and... Lees meer.

A first-stop reference on proteins associated with amyloidosis. This book is the first to present a systematic overview of all known fibril-forming proteins including their biochemical characteristics and pathophysiology. It considers the clinically recognized amyloid... Lees meer.

Markov State Models MSM sind der Goldstandard zur Modellierung biomolekularer Dynamik da sie die Identifizierung und Analyse metastabiler Zust nde erm glichen. Markov State Models MSM sind der Goldstandard zur Modellierung biomolekularer Dynamik da sie die Ident... Lees meer.

This detailed volume focuses on methods for the characterization of aggregation processes that lead to the formation of amyloid fibrils and amyloid oligomers which feature in the etiology of a variety of human disorders collectively known as amyloidoses. This detai... Lees meer.

This third edition volume expands on the previous editions with many new chapters that cover the latest techniques and topics that were not addressed in the previous volumes. The chapters in this book are divided into three parts. Part One covers in vitro assays that f... Lees meer.

This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins protein folding disorders and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techn... Lees meer.

Proceedings of the VIth International Symposium on Amyloidosis held in Oslo Norway 5-8 August 1990. Both scientifically and socially the Vlth International Symposium on Amyloidosis August 5 - 8 1990 in Oslo was a great success. There were three and a half intens... Lees meer.

This detailed volume introduces different methods to assess the structure and folding of bacterial amyloids and analyze their functions either in vitro or in vivo. This detailed volume introduces different methods to assess the structure and folding of bacterial amylo... Lees meer.

Early Stage Protein Misfolding and Amyloid Aggregation Volume 329 the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology including articles that address the structu... Lees meer.

... Lees meer.

Consequences of Intracellular Amyloid in Alzheimer s Disease addresses one of the more currently unresolved aspects confounding Alzheimer s research the significance of intraneuronal amyloid. It seeks to explain some of the unresolved questions concerning intracellula... Lees meer.

This volume of the Subcellular Biochemistry series is the result of the long-standing research interest of the editor in the molecular mechanism underlying Alzheimer s disease and other amyloid diseases indicated also by the earlier book in the series Volume 38 devot... Lees meer.

Amyloid diseases are characterized by the deposition of insoluble fibrous amyloid proteins. The word amyloid indicates a starch-like compound and though a misnomer continues to be the accepted term for this group of protein conformational disorders. The second edit... Lees meer.

Highlighting the latest and the most timely aspects of Alzheimer s disease research this text should enable scientists in related research fields as well as physicians working with Alzheimer s disease patients to obtain a quick and complete overview of the current st... Lees meer.