This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism namely the aggregation and deposition of insoluble proteinaceous lesions termed amyloid . Examples of cerebral amyloid disorders include common neuro... Lees meer.

Amyloid-forming proteins are implicated in over 30 human diseases. Substantial evidence suggests these lesions are the end state of aberrant protein folding whereas the actual disease-causing culprits likely are soluble non-fibrillar assemblies preceding the aggregates... Lees meer.

Amyloid-forming proteins are implicated in over 30 human diseases. Substantial evidence suggests these lesions are the end state of aberrant protein folding whereas the actual disease-causing culprits likely are soluble non-fibrillar assemblies preceding the aggregates... Lees meer.

Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer s disease-related dementia and Parkinson s disease as well as other less prevalent conditions like Huntington s disease cerebral amyloid angiopathy and the transmissible pr... Lees meer.

Amyloid-forming proteins are implicated in over 30 human diseases. The proteins involved in each disease have unrelated sequences and dissimilar native structures but they all undergo conformational alterations to form fibrillar polymers. The fibrillar assemblies accum... Lees meer.

This book reviews current research on the important processes involved in neurodegenerative diseases e.g. Alzheimer s disease and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors and... Lees meer.

Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer s disease-related dementia and Parkinson s disease as well as other less prevalent conditions like Huntington s disease cerebral amyloid angiopathy and the transmissible pr... Lees meer.

Many untreatable neurodegenerative human disorders like Parkinson s Alzheimer s and prion diseases are associated with the aggregation of misfolded or natively unfolded proteins into amyloid fibrils. Cells have adapted two main sophisticated quality-control measures... Lees meer.

This book reviews current research on the important processes involved in neurodegenerative diseases e.g. Alzheimer s disease and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors and g... Lees meer.