Stress signalling and breast cancer development

Rubriek: Textual/Printed/Reference Materials - Boek

Prijs: € 62.99

Rating: 0/5

☆

☆

☆

☆

☆

Verzending:
2 - 3 weken

Breast cancer is one of the major causes of premature mortality in women. Research suggests that psychological stress may be a contributing factor to breast cancer development. However, the molecular mechanisms responsible for such an association have yet to be clearly defined. This research work outlines the current state of knowledge on the relationship between stress and breast cancer and focuses on identifying novel molecular signals which may contribute to the effect of stress on breast physiology. With the help of molecular techniques, The Breast Cancer Susceptibility Gene 1 (BRCA1), an important regulator of the genetic processes responsible for tumor development, is identified as a target of stress signalling. In addition, the currently unknown role of genetic modifiers in the relationship between stress and breast cancer is addressed through the development of an epidemiological study examining if stress- susceptible individuals are at an increased risk of developing breast cancer. An integrative model, incorporating genetic stress susceptibility and downstream changes in the expression and activity of molecular regulators is proposed.

• 1 Bekijk alle specificaties

Taal: en

Bindwijze: Paperback

Oorspronkelijke releasedatum: 10 maart 2011

Aantal pagina's: 160

Illustraties: Nee

Hoofdauteur: Lilia Antonova

Hoofduitgeverij: Vdm Verlag

Extra groot lettertype: Nee

Product breedte: 152 mm

Product hoogte: 9 mm

Product lengte: 229 mm

Studieboek: Ja

Verpakking breedte: 152 mm

Verpakking hoogte: 10 mm

Verpakking lengte: 229 mm

Verpakkingsgewicht: 245 g

EAN: 9783639316681

---