Amyloid protein precursor in development aging and alzheimer s disease

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This is a summary of the last ten years' research on Alzheimer's disease. Genetic mutations in the gene with codes for amyloid precursor protein (APP) have now been shown to cause Alzheimer's disease in some families. Other genetic loci are now being discovered which relate to Alzheimer's disease in families. Understanding the normal structure and function of the APP gene product will eventually provide avenues for developing specific therapeutic strategies targeted at the amyloid deposition in the brain. Drugs which can inhibit or dissolve the amyloid, affect the synthesis and proteolysis of APP, or which regulate the activity of the APP gene, are explored in the text.

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Oorspronkelijke releasedatum: 24 juni 1994

Aantal pagina's: 277

Hoofdredacteur: Colin L. Masters

Tweede Redacteur: Konrad Beyreuther

Co Redacteur: Yves Christen

Hoofduitgeverij: Mairdumont Gmbh & Co. Kg

Verpakking breedte: 155 mm

Verpakking hoogte: 235 mm

Verpakking lengte: 235 mm

Verpakkingsgewicht: 545 g

EAN: 9783540577881

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