A phenomenological mathematical modelling framework for the degradation of biore
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This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation.
This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation.
Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation.
Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.
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Taal: en
Bindwijze: Hardcover
Oorspronkelijke releasedatum: 16 april 2019
Aantal pagina's: 325
Illustraties: Nee
Hoofdauteur: Ismael Moreno-Gomez
Hoofduitgeverij: Springer Nature Switzerland AG
Fabrikantgegevens: De informatie van de fabrikant is momenteel niet beschikbaar.
Editie: 1
Extra groot lettertype: Nee
Product breedte: 155 mm
Product lengte: 235 mm
Studieboek: Nee
Verpakking breedte: 155 mm
Verpakking hoogte: 22 mm
Verpakking lengte: 235 mm
Verpakkingsgewicht: 0.72 kg
EAN: 9783030049898