Chemistry of a unsaturated trifluoromethyl ketones

Rubriek: Textual/Printed/Reference Materials - Boek

Prijs: 214.08 Nu voor: € 59.82

Rating: 0/5

☆

☆

☆

☆

☆

Verzending:
1 - 2 weken

Subject Scope: Organofluorine chemistry. This book addresses the fact of the trifluoromethyl group, due to its unique stereoelectronic properties, as a very important substituent in medicinal chemistry. The trifluoromethyl group usually increases lipophilisity of the molecules improving their transport characteristics in vivo. Furthermore, the durability of C-F bond comparing with N-I bond (116 and 100 kcal/mol correspondingly) allows to avoid undesirable metabolic transformations. The introduction of trifluoromethyl group into bioactive molecules becomes very important direction in pharmaceutical studies that stimulates the works directed to elaboration of synthetic methodology for various compounds containing trifluoromethyl group. Due to all these factors organofluorine chemistry has been vigorously developing during the last two decades.

• 1 Bekijk alle specificaties

Oorspronkelijke releasedatum: 01 september 2007

Aantal pagina's: 143

Hoofdauteur: Elizabeth S Balenkova

Tweede Auteur: Sergey V Druzhinin

Co Auteur: Valentine G. Nenajdenko

Hoofduitgeverij: Nova Science Publishers

Editie: illustrated edition

Product breedte: 260 mm

Product lengte: 180 mm

Verpakking breedte: 260 mm

Verpakking hoogte: 180 mm

Verpakking lengte: 180 mm

Verpakkingsgewicht: 496 g

EAN: 9781600219139

---