In situ hybridization is a technique of molecular biology that is used to localize the genetic machinery involved in protein making. It is particularly important in the study of the mechanisms underlying cellular function and disease. This applications-oriented volume covers all aspects of in situ hybridization, from the basic principles of molecular biology, through many recent methodological advances, to the most up-to-date muses in medical pathology. With contributions by leaders in the field, this work will be a primary resource for all those using the technique. The book is spiral-bound for added convenience, and includes a number of color figures to illustrate the material presented in the text.